The microwave-size instrument at Lila Sciences in Cambridge, Massachusetts, doesn’t look all that different from others that I’ve seen in state-of-the-art materials labs. Inside its vacuum chamber, the machine zaps a palette of different elements to create vaporized particles, which then fly through the chamber and land to create a thin film, using a technique called sputtering. What sets this instrument apart is that artificial intelligence is running the experiment; an AI agent, trained on vast amounts of scientific literature and data, has determined the recipe and is varying the combination of elements. Later, a person will walk the samples, each containing multiple potential catalysts, over to a different part of the lab for testing. Another AI agent will scan and interpret the data, using it to suggest another round of experiments to try to optimize the materials’ performance. This story is part of MIT Technology Review’s Hype Correction package, a series that resets expectations about what AI is, what it makes possible, and where we go next. For now, a human scientist keeps a close eye on the experiments and will approve the next steps on the basis of the AI’s suggestions and the test results. But the startup is convinced this AI-controlled machine is a peek into the future of materials discovery—one in which autonomous labs could make it far cheaper and faster to come up with novel and useful compounds. Flush with hundreds of millions of dollars in new funding, Lila Sciences is one of AI’s latest unicorns. The company is on a larger mission to use AI-run autonomous labs for scientific discovery—the goal is to achieve what it calls scientific superintelligence. But I’m here this morning to learn specifically about the discovery of new materials. Lila Sciences’ John Gregoire (background) and Rafael Gómez-Bombarelli watch as an AI-guided sputtering instrument makes samples of thin-film alloys.CODY O’LOUGHLIN We desperately need better materials to solve our problems. We’ll need improved electrodes and other parts for more powerful batteries; compounds to more cheaply suck carbon dioxide out of the air; and better catalysts to make green hydrogen and other clean fuels and chemicals. And we will likely need novel materials like higher-temperature superconductors, improved magnets, and different types of semiconductors for a next generation of breakthroughs in everything from quantum computing to fusion power to AI hardware.