The US Secret Service has already arrived in the Pakistani capital to make security arrangements ahead of his visit, which marks the most significant face-to-face, high-level US-Iran contact since 1979.
The American delegation is expected to arrive in Islamabad on Friday, with negotiations likely to last for one day over the weekend. Vance – who concluded a visit to Budapest on Thursday – will be joined by US President Donald Trump’s special envoy, Steve Witkoff, and his son-in-law, Jared Kushner.
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