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Michelle Suter has worn mostly big and baggy clothing for years. The 63-year-old retiree who lives in a suburb of St. Louis, Missouri gave away her favorite sundresses and other form-fitting outfits, thinking she’d never be those smaller sizes again.

Now, after losing about 28 pounds while taking GLP-1 drug Wegovy, she said she has started to dream of her new wardrobe.

“That’s part of the excitement — to wear things that are new and fit rather than old clothes that you can tie the drawstring tighter,” she said.

As more U.S. consumers take weight loss and diabetes drugs and shed significant pounds, fashion brands and retailers could have a fresh opportunity — selling to shoppers like Suter who plan to refresh their closets.