At least 25 people have now been confirmed killed in Pakistan during the violent weekend protests over the killing of Iran's supreme leader has reached at least 25, the AFP reported Monday.

Demonstrations erupted in several major cities in Pakistan, including the southern megacity of Karachi, where some protesters attempted to storm American diplomatic buildings.

An Agence France-Presse (AFP) journalist witnessed hundreds of pro-Iranian protesters trying to enter the United States consulate, prompting clashes with police.

At least 10 deaths were reported and over 70 were injured, the office of the Karachi police surgeon said, while a hospital toll seen by AFP listed nine people as having died from gunshot wounds.

In Pakistan's northern Gilgit-Baltistan region, at least 13 people were killed in clashes between protesters and police, officials said.