March 1 (UPI) -- Some 22 people were killed amid anti-U.S. protests in Pakistan Sunday, following the U.S.-Israeli offensive Saturday that left 200 people dead.

In Karachi, at least 10 people were killed as they attempted to storm the U.S. Consulate, while two were killed in Islamabad and another 10 killed in Gilgit-Baltistan, the New York Times reported.

"When Iran is attacked, we feel our faith, our identity and our very existence are being targeted," a student protestor in Karachi said, The Times reported.

The country's supreme leader, Ayatollah Ali Khamenei was among the dead following the U.S. and Israeli attacks.

In response, protests are swelling across the region, including in Iraq and India.