Israel and the U.S. embarked on an operation to remove the existential threat posed by the terrorist regime in Iran, Israeli Prime Minister Benjamin Netanyahu said in a video message to citizens.

"I thank our great friend, President Donald Trump, for his historic leadership," Netanyahu said.

Also read: Israel-Iran conflict LIVE updates

"For 47 years, the Ayatollah regime has called for 'Death to Israel' and 'Death to America.' It has spilled our blood, murdered many Americans, and massacred its own people," the Israeli Premier said.

"This murderous terrorist regime must not be allowed to arm itself with nuclear weapons that would enable it to threaten all of humanity," he stressed.