Snow, freezing rain and sleet threaten to snarl travel for those heading home after the Christmas holiday across parts of the Great Lakes, Northeast and Mid-Atlantic, forecasters said.

Snow is expected to develop on Christmas Day in the Northeast and later in the day in the upper Midwest. By Dec. 26, a second system will bring a wintry mix to a stretch from Michigan across Pennsylvania and into the upper Mid-Atlantic, the National Weather Service said.

"This winter storm is likely to generate treacherous travel conditions and delays following Christmas Day," the weather service said.

An estimated 122.4 million Americans are expected to travel at least 50 miles over the end-of-year holiday season, including nearly 110 million who will travel by car, according to AAA.

The fast-moving storm could impact millions with travel disruptions and power outages, AccuWeather reported. Several inches could accumulate on roads. A buildup of ice and snow can also cause downed tree limbs and power lines.