Women who stop taking a GLP-1 weight loss/diabetes medication just prior to a pregnancy appear to be at higher odds for excess weight gain and complications while pregnant, new research shows.
As the study authors pointed out, potential risks to the fetus of using a GLP-1 while pregnant remain unclear, so current recommendations advise discontinuing the drugs prior to or during a pregnancy.
However, doing so may bring about its own hazards, concluded a team from Mass General Brigham in Boston.
"Additional studies are needed on the balance of pre-pregnancy benefits of GLP-1s with the risks associated with interrupting them for pregnancy," said study senior author Dr. Camille Powe. She's a Mass General Brigham endocrinologist and co-director of the Diabetes in Pregnancy Program at Massachusetts General Hospital.
Related
