The international team discovered how the immune system is kept in check to prevent it attacking the body.
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The Nobel Prize in physiology or medicine has been awarded to Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi for their work on the functioning of the human immune system.
The award, announced by Sweden’s Karolinska Institute on Monday, will be presented to the trio in December for “their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body”.










