Britain's new interim ambassador to the US has been revealed as a career diplomat who suffered tragedy when his wife nearly died from a brain haemorrhage.James Roscoe - who has worked for Queen Elizabeth II, Tony Blair and Gordon Brown - took over immediately today as the UK's representative in Washington.It comes after Lord Mandelson was sacked as ambassador following emails that revealed the depth of his relationship with paedophile financier Jeffrey Epstein.Mr Roscoe, 49, will oversee Donald Trump's second state visit to the UK next Wednesday with only one week to go until the US President arrives in Windsor.He lives in Washington with his 43-year-old wife Clemency Burton-Hill - who is a BBC presenter, musician and actress - and their two young sons Tomos and Joe.Ms Burton-Hill suffered a brain haemorrhage in January 2020 caused by an abnormal connection between the arteries and veins in her brain which left her in a coma.She found her speech started slurring during a meeting in New York before she suddenly blacked out - and woke up in a hospital bed 17 days later.Ms Burton-Hill, who met her husband in Sierra Leone in 2006 and married him in 2008, was left unable to see, talk or walk but defied medical expectation to relearn all three. Clemency Burton-Hill and James Roscoe attend the Hay Festival in Wales in May 2013 Clemency Burton-Hill with neurosurgeon Dr Christopher Kellner in March 2020 at Mount Sinai West Hospital in New York City after a cranioplasty operation to replace half of her skullShe paid tribute to Mr Roscoe as her 'ever supportive husband' in The Mail On Sunday's You magazine in August 2020, writing: 'I do choose life. Every day. I choose life in all its complexity; aware of its beauty, its pain, its hope, its fragility, its love.'Life, I believe, is a gift of unimaginable proportions. I don't know what the future holds - for me or the world - but I have faith in the extraordinary power of humanity.'Her emergency surgery, near-death experience and subsequent recovery also featured in a BBC Arena documentary called My Brain: After the Rupture in March.Mr Roscoe and Ms Burton-Hill met in 2006 in Sierra Leone, where he had been working at the British High Commission and where she had travelled to write an article for The Spectator.Cambridge graduate Ms Burton-Hill, who played the king's would-be girlfriend in the fictional ITV series The Palace, is the daughter of the BBC's former arts chief Humphrey Burton.Mr Roscoe and Ms Burton-Hill married in 2008 but were separated for more than two months the following year when he moved to New York to take up a job with the UN in the July, while work stopped her from joining him until September. They had their first son Tomos in 2014.Mr Roscoe is known for his time in the Royal Household as chief spin doctor or 'communications secretary' to the late Queen Elizabeth II from 2013 to 2016.The Telegraph revealed at the time of his appointment in 2012, initially as the Queen's deputy press secretary and head of news, that he would be paid £70,000 'plus benefits' by Buckingham Palace. The 49-year-old also spent time at Downing Street as chief press officer in the Prime Minister's office for Tony Blair and Gordon Brown from 2006 to 2009. James Roscoe and Clemency Burton-Hill at Washington Market Park in New York in June 2020 James Roscoe in Windsor during Queen Elizabeth II's 90th birthday celebrations in April 2016He was made deputy head of mission at the British Embassy in Washington in July 2022 and before that was UK ambassador to the UN General Assembly from 2019. Mr Roscoe has previously focused on areas such as sanctions and counter-terrorism issues and has had postings to Freetown in Sierra Leone and Basra in Iraq.In 2016 Mr Roscoe - once one of the Queen's closest confidants - hit the headlines when a leaked email reignited the row over claims Buckingham Palace backed Brexit. The memo revealed by The Mail On Sunday showed his excited reaction to his new job of helping Boris Johnson make a success of taking Britain out of the European Union. Announcing his move to become the Foreign Secretary's Brexit spin doctor, Mr Roscoe said he could not wait to get stuck in as Mr Johnson's 'Head of Post Referendum Communications Unit'.Mr Roscoe said at the time that Britain was 'an extraordinary country with an incredible Sovereign' and would 'thrive and prosper' when it had broken free of Brussels.His pro-Brexit rallying cry came four months after a storm over claims that the Queen had said she backed Brexit.At a dinner with coalition ministers Michael Gove and Nick Clegg, the Queen is said to have made it clear that she believed the UK would be better off out of the EU, although she denied it. Lord Mandelson and Prime Minister Sir Keir Starmer at an event in Washington DC in February Lord Mandelson wears a white dressing gown as he chats with Jeffrey Epstein in around 2002As for Lord Mandelson, Sir Keir Starmer made the decision to sack him today after emails showed the peer sent supportive messages even as Epstein faced jail for sex offences.The Foreign Office said the emails showed that 'the depth and extent of Peter Mandelson's relationship with Jeffrey Epstein is materially different from that known at the time of his appointment'.He has now been withdrawn as ambassador with immediate effect.Lord Mandelson is reported to have told Epstein to 'fight for early release' shortly before he was sentenced to 18 months in prison, and told him 'I think the world of you', the day before he began his sentence for soliciting prostitution from a minor in June 2008.The Prime Minister had defended Lord Mandelson until the emergence of the emails, insisting he had gone through a proper vetting process and had helped build a successful relationship with Donald Trump's White House.Lord Mandelson's friendship with Epstein had been known about, but Bloomberg and The Sun published emails showing that the relationship continued after the crimes committed by the financier had emerged.Foreign Office minister Stephen Doughty told MPs that information had not been known when Lord Mandelson was appointed.