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A quiet revolution in care is helping patients with cardiac amyloidosis, a form of heart failure that long stumped doctors.

By Simar Bajaj

When James Hicks, 75, was diagnosed with heart failure, it felt like the beginning of the end.

Mr. Hicks, a former railroad worker from Rogers, Ark., had quietly dealt with various health problems, from carpal tunnel syndrome in both arms to dual knee replacements. But now his heart was giving out, and the doctors chalked it up to the wear and tear of old age. “There’s just not exactly a surgery to fix this,” he said.