Aug. 4 (UPI) -- People with multiple sclerosis, or MS, begin experiencing new health issues up to 15 years before the classic signs of the illness appear, Canadian research shows.

"MS can be difficult to recognize as many of the earliest signs -- like fatigue, headache, pain and mental health concerns -- can be quite general and easily mistaken for other conditions," study senior author Helen Tremlett noted.

"Our findings dramatically shift the timeline for when these early warning signs are thought to begin, potentially opening the door to opportunities for earlier detection and intervention," said Tremlett, a professor of neurology at the University of British Columbia in Vancouver.

Her team published its findings Friday in JAMA Network Open.

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