Tibetans adapted to live at high altitudes where oxygen is scarce; study suggests ancient interbreeding with an extinct human population may have given their ancestors a genetic advantage to survive in one of planet’s harshest environments

Tibetan highlander populations have distinct genetic variants in proximity to the EPAS1 gene, facilitating their adaptation to high altitudes with low oxygen availability. These genetic traits prevent excessive production of red blood cells, which would otherwise thicken the blood. Research indicates these variants likely arose through ancient interbreeding with Denisovans. Over generations, natural selection has favored these DNA sequences, enhancing survival in harsh environments.

Raccontata daeconomictimes.indiatimes.com