Integrative 3D epigenomic profiling of four glial cell types from the mid-gestation human cortex reveals cell-type-specific regulatory elements and chromatin interactions that illuminate the roles of non-coding variants in neuropsychiatric disease and human-specific cortical evolution.

UCLA researchers have discovered two powerful influences that help guide how the human brain forms before birth. Radial glia, stem cells responsible for producing much of the…

Integrative 3D epigenomic profiling of four glial cell types from the mid-gestation human cortex reveals cell-type-specific regulatory elements and chromatin interactions that…