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A tumour-derived organoid biobank maps cancer gene dependencies - Nature
A clinically annotated multi-omic organoid resource with matched tumour samples from 256 patients across 5 cancers maps gene dependencies, reveals subtype-specific vulnerabilities and uncovers treatment-driven changes, expanding mechanistic insight and models for precision oncology.
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A tumour-derived organoid biobank maps cancer gene dependencies - Nature
A clinically annotated multi-omic organoid resource with matched tumour samples from 256 patients across 5 cancers maps gene dependencies, reveals subtype-specific vulnerabilities…
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A compendium of next-generation patient-derived models for diverse cancers - Nature
The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and…
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A dependency map enhanced with next-generation 3D cancer models - Nature
Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and genomic…