An FDA panel is reviewing seven peptides for potential approval, sparking concerns about their widespread use in compounding pharmacies and the gray market.

The committee will discuss whether compounding pharmacies can make the peptides in question. But FDA scientists say there’s little — if any — evidence they work in humans.

As regulators weigh whether pharmacies can legally compound wellness peptides, companies are preparing for a repeat of the GLP-1 boom—only this time with even murkier science.