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AI identifies interactions in CRISPR complexes to improve specificity of DNA editing
AlphaFold3 predictions of the molecular contacts made by a genome-editing enzyme have been used to improve the enzyme’s selectivity for target DNA sequences.
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nature.com
Timeline cronologica
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AI identifies interactions in CRISPR complexes to improve specificity of DNA editing
AlphaFold3 predictions of the molecular contacts made by a genome-editing enzyme have been used to improve the enzyme’s selectivity for target DNA sequences.
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Precise DNA base editing using AlphaFold3-based contact modelling - Nature
ContactSeek is an AlphaFold3-driven model that can improve the precision of genome-editing tools.