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Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Michigan State University researchers have identified how ovarian cancer cells become resistant to chemotherapy and discovered a protein that, when blocked, can restore the drug's effectiveness.

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medicalxpress.comStai leggendo9 g fa

Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Researchers identified TPPP3 protein driving cisplatin resistance in ovarian cancer; blocking it restores drug sensitivity and predicts treatment outcomes. This enables TPPP3-targeted therapies and biomarker-guided personalization, improving existing chemotherapy efficacy rather than requiring new agents.

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infobae.com8 g fa

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia

Un trabajo de la Universidad Estatal de Michigan, publicado en Cell Reports, asocia la sobreexpresión de una proteína con menor supervivencia y muestra en laboratorio que su ausencia reactiva la respuesta tumoral al…

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Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia

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Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia