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Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Michigan State University researchers have identified how ovarian cancer cells become resistant to chemotherapy and discovered a protein that, when blocked, can restore the drug's effectiveness.

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medicalxpress.comStai leggendo1 mese fa

Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Researchers identified TPPP3 protein driving cisplatin resistance in ovarian cancer; blocking it restores drug sensitivity and predicts treatment outcomes. This enables TPPP3-targeted therapies and biomarker-guided personalization, improving existing chemotherapy efficacy rather than requiring new agents.

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infobae.com1 mese fa

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia

Un trabajo de la Universidad Estatal de Michigan, publicado en Cell Reports, asocia la sobreexpresión de una proteína con menor supervivencia y muestra en laboratorio que su ausencia reactiva la respuesta tumoral al…

Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia

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Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it

Identifican cómo el cáncer de ovario se vuelve resistente a la quimioterapia