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A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics - Nature
In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally evolved combination therapy.
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nature.com
A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics - Nature
In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally…
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‘Megacluster’ of genes enables bacteria to make potent antibiotic mixture
Soil bacteria make cocktails of molecules that synergistically inhibit the growth of microbial pathogens — suggesting a strategy for tackling antibiotic-resistant infections.
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arstechnica.com
Antibiotic "megacluster" discovery provides new strategy to fight superbugs
It's "an exciting advance in efforts to restock the antibiotic arsenal."