SkyCity Adelaide reaches a settlement agreement with South Australia's Liquor and Gambling Commissioner in what the premier says is possibly the biggest fine handed out in the state's history.

Casino operator SkyCity Entertainment says it has reached an agreement to finally resolve all regulatory matters related to its Adelaide Casino.

The settlement was lower than what one analyst expected.

Under an agreement struck with the gambling regulator, SkyCity must also appoint non-executive directors and a local chief executive.

SkyCity Adelaide reaches a settlement agreement with South Australia's Liquor and Gambling Commissioner in what the premier says is possibly the biggest fine handed out in the…