US stocks opened lower as rising crude oil prices and renewed Middle East tensions pressured sentiment, after reports of Iranian missile activity near Kuwait and Bahrain. Dow, S&P 500 and Nasdaq slipped at open, while concerns over new US tariff proposals added to risk-off mood despite strong AI-led earnings support.

U.S. stock futures were mixed on Wednesday, after a record close on Tuesday, as the Dow Jones and S&P 500 advanced but the Nasdaq 100 fell.

(Bloomberg) -- US stocks struggled to build on record gains as growing strains on the ceasefire between the US and Iran sent oil prices higher for a third straight day.

US stocks opened lower as rising crude oil prices and renewed Middle East tensions pressured sentiment, after reports of Iranian missile activity near Kuwait and Bahrain. Dow, S&P…