Randomized trial results of the experimental GLP-1, GIP, and glucagon drug shows that it may be too effective, while causing a whopping 11% of participants at the highest dose to drop out because of the severity of the side effects. In Optimizer, Victoria Song covered TikTok influencers pushing grey market knockoffs of “Ratatouille” and attempted to find out what was actually in them. (Please don’t buy shady “Retatrutide” from the internet.)

A once-weekly triple receptor agonist conferred up to 28.3% weight loss at 80 weeks for adults with overweight or obesity, according to topline results from a phase 3 trial. As…

While drugs such as Wegovy target a single gut hormone, retatrutide is among a new class of GLP-1 drugs that aims at three hormone receptors

Randomized trial results of the experimental GLP-1, GIP, and glucagon drug shows that it may be too effective, while causing a whopping 11% of participants at the highest dose to…