Stay up to date with notifications from The IndependentNotifications can be managed in browser preferences.AllNewsSportCultureLifestyleThe Makerfield by-election, where Andy Burnham is standing as Labour’s candidate, has been confirmed for Thursday, 18 June. Burnham, the Mayor of Greater Manchester, is seen as a potential challenger to Keir Starmer's leadership, but would need to win the seat before launching any formal bid. Keir Starmer's political future is in doubt following dire local election results, calls for his resignation from Labour MPs, and a series of government resignations. Wes Streeting, who resigned as health secretary, warned that Labour is losing the fight against nationalism and risks handing power to Reform UK unless it changes course. Streeting, who intends to stand in any future leadership contest, stressed the importance of Labour fighting for young people and addressing future challenges like the 'AI jobs apocalypse'. In fullMakerfield by-election date set as Andy Burnham eyes return to Westminster and Labour leadership challengeThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in

Reform, which won more than 50% of the local election vote, is likely to focus heavily on immigration and Brexit

The Mayor of Manchester has several obstacles to overcome on the long road to Westminster