Brain-wide transcriptomic profiling in mice reveals that reproductive experience remodels the maternal brain by altering dopamine dynamics in the dorsal hippocampal formation, causing dopamine-dependent histone post-translational modifications, and thereby changes in gene expression and behaviour.

Brain-wide transcriptomic profiling in mice reveals that reproductive experience remodels the maternal brain by altering dopamine dynamics in the dorsal hippocampal formation,…

In mice, motherhood induces transcriptional changes in the brain that endure beyond short-term hormonal shifts. Postpartum stress disrupts these patterns.