Whichever way it goes, the by-election in Makerfield has the potential to shape the UK for decades - potentially propelling Labour into a new era or causing a catastrophic crisis

Greater Manchester mayor’s gamble on a byelection could catapult him into the Labour leadership — or end his career — as pressure mounts on Keir Starmer

Winning the Makerfield by-election could be a major challenge for Andy Burnham, as he is eyeing up a new role in Westminster.

How a contest to become PM is triggered, and Andy Burnham’s chances in the Makerfield byelection

The question of who the next Prime Minister will be could lie in the hands of voters in the soon-to-be vacated Makerfield seat.

Whichever way it goes, the by-election in Makerfield has the potential to shape the UK for decades - potentially propelling Labour into a new era or causing a catastrophic crisis

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Reform, which won more than 50% of the local election vote, is likely to focus heavily on immigration and Brexit