The war between the U.S. and Iran is threatening to widen and jolt global energy supplies.

Global investors reacted to the weekend strikes in the Middle East by selling U.S. stocks in futures markets. Some assets may benefit, however.

Oil futures on Monday jumped by over 8%, with West Texas Intermediate futures and Brent trading at $72.52 and $79.04 per barrel respectively.

The war between the U.S. and Iran is threatening to widen and jolt global energy supplies.

Brent crude rose by 13% during early trading and stock markets came under pressure as US-Israeli strikes on Iran raised fears of disruption

Brent crude is up by 9 percent amid supply concerns as Trump says strikes on Iran could last weeks.

Monday marked the third day of the conflict with Iran after joint U.S.-Israel military strikes killed Supreme Leader Ayatollah Ali Khamenei over the weekend.

U.S. stock index futures fell on Tuesday as investors assessed the fallout of U.S. and Israeli strikes on Iran and the repercussions it could have on inflation and global trade.