The supreme leader finds himself isolated by the losses of his key security advisers, raising the risk of strategic miscalculations.

Israel has already taken out top ranking officials including the chief of staff of the Iranian military and the commander-in-chief of the IRGC since the conflict erupted on Friday

The supreme leader finds himself isolated by the losses of his key security advisers, raising the risk of strategic miscalculations.

Iran's 86-year-old Supreme Leader Ayatollah Ali Khamenei cuts an increasingly lonely figure.

With the heavy losses inflicted by Israel's attack adding to pre-existing pressures, the Islamic republic has never looked weaker. But talk of regime change seems premature.

Iranian opposition is divided and there is no guarantee new rulers would be any less hardline, analysts say.