Health-care companies fell, but not by as much as the broad market, as traders rotated into sectors less sensitive to inflation and fuel costs.

Tyra Biosciences fell sharply after the performance of a bladder-cancer drug candidate in a mid-stage clinical trial disappointed investors.

Johnson & Johnson, which is also developing a bladder-cancer treatment, fell slightly.

Write to Rob Curran at rob.curran@dowjones.com

(END) Dow Jones Newswires