— Findings suggest clinicians view these drugs as safe and effective in this population

September 3, 2026

• 3 min read

People with serious mental illness (SMI) face high cardiovascular risk, making GLP-1 drugs a potential tool to reduce mortality.Prescription rates rose significantly among all adults with an underlying GLP-1-indicating condition from 2018 to 2024, but was higher for adults with SMI.Findings support the idea that clinicians view these medications as safe and effective for people with SMI, the researchers said.

Adults with serious mental illness (SMI) received GLP-1 drug prescriptions at higher rates than those without SMI from 2018 to 2024, an analysis of U.S. insurance claims data showed.