August 25, 2026
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The FDA approved two zanidatamab-hrii-based regimens as first-line treatment for adults with unresectable locally advanced or metastatic HER2-positive gastroesophageal adenocarcinoma. Zanidatamab-hrii (Ziihera, Jazz Pharmaceuticals) received approval in combination with fluoropyrimidine- and platinum-containing chemotherapy, and in combination with both fluoropyrimidine- and
August 25, 2026
2 min read
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Ziihera can now be used as an initial treatment for all HER2-positive gastroesophageal adenocarcinomas, dramatically expanding…

FDA approves Jazz Pharmaceuticals' Ziihera combinations for first-line treatment of HER2-positive gastroesophageal adenocarcinoma.

Jazz's Ziihera wins FDA nod for frontline HER2+ gastric cancer, clearing use with chemo, with or without BeOne's Tevimbra.

Jazz Pharmaceuticals’ bispecific antibody Ziihera has gained FDA approval for first-line HER2-positive stomach cancer, unlocking…

FDA approves JAZZ's Ziihera-containing combination regimens for HER2-positive gastroesophageal adenocarcinoma. JAZZ stock drops…

Bispecific antibody plus chemo with or without tislelizumab improves OS, PFS versus trastuzumab