Police in South Africa have arrested five people for allegedly operating a multimillion-dollar crystal methamphetamine manufacturing operation on a farm in Limpopo province.

During the operation, they confiscated drugs and laboratory equipment with an estimated street value of over $37 million, as well as an undisclosed amount of cash.

"The discovery has exposed an alleged sophisticated, industrial-scale operation believed to have been established for the manufacture of dangerous illicit substances destined for distribution," the police said.

Officials say the suspects, aged between 20 and 47, comprise two Mexican nationals, two Zimbabweans, and a Malawian.

The overnight raid follows a series of drugs busts over the past months involving Mexican nationals, leading authorities to suspect Latin American cartels are expanding into Africa.