Will Mike Evans Play in Week 1? (Getty Images)Mike Evans’ latest injury has added another concern to a San Francisco 49ers roster already dealing with several health issues. The veteran wide receiver first missed time with a quad strain earlier this month, then returned for a joint practice before leaving another session with his left quad wrapped in ice. That naturally raised questions about his availability for Week 1 against the Los Angeles Rams. Still, the latest comments from Kyle Shanahan and reports from the 49ers beat suggest the team is not overly worried about the issue.Will Mike Evans play in Week 1?There is no certainty as of now, but there is still hope. For now, there is more reason for optimism than concern surrounding Evans. The 49ers signed the six-time Pro Bowler to a three-year, $42.4 million contract after his 12 seasons with the Tampa Bay Buccaneers, expecting him to become an important part of their passing attack.His transition to Kyle Shanahan’s offense has not been completely smooth, though. Evans suffered a quad strain on August 3 and missed several practices before returning for San Francisco’s joint session with the Tennessee Titans on August 11.The bigger concern came a week later. During the 49ers’ joint practice with the Los Angeles Chargers ahead of their second preseason game, Evans was pulled from the session and had his left quad reportedly treated with ice. There was no clear indication of a new injury or exactly what caused the discomfort.San Francisco beat reporter Matt Maiocco offered some relief, reporting, “Kyle Shanahan said Mike Evans was just experiencing some tightness. He does not think it’s anything serious.”ESPN NFL reporter Nick Wagoner also suggested there was little immediate reason for alarm, saying Shanahan “didn’t sound concerned, nor did it look particularly painful for Evans, but we’ll see where he is when the team returns to practice this weekend. Hard to imagine he will play (or would have) on Thursday night.”That approach makes sense for a veteran receiver who has already missed significant time. Evans appeared in only eight games last season because of injuries, making his health an important part of San Francisco’s plans.The 49ers do have alternatives. De’Zhaun Stribling has impressed during training camp and the preseason, while Deebo Samuel Sr. and Demarcus Robinson remain part of the receiver group. Christian Kirk is also dealing with an injury, however, which makes Evans’ availability even more valuable.For now, the expectation is that Evans should be ready for Week 1, provided the quad responds well when the 49ers return to practice. San Francisco will likely avoid pushing him unnecessarily in the preseason. The real test will come when the team begins preparing specifically for the Rams and Evans’ status becomes clearer.