A new generation of drugs could transform the lives of people with narcolepsy and offer hope of future treatments for ADHD and depression.Orexins help regulate wakefulness, as well as attention, motivation and the brain’s reward system. This month, the US Food and Drug Administration approved the first orexin agonist treatment for narcolepsy. Oveporexton (sold as Orzeyful) is designed to target the cause of the chronic sleep disorder, rather than treat the symptoms with stimulants.
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