The San Francisco 49ers and Los Angeles Chargers have shared a joint practice this week, and now the two California teams will face off in Week 2 of the preseas
49ers vs. Chargers Prediction, Odds, Spread, Trends for NFL Preseason Week 2
Iain MacMillan|
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The San Francisco 49ers are favored against the Los Angeles Chargers in Week 2 of the NFL Preseason. | IMAGN IMAGES via Reuters Connect
In this story:
Week 1 of the 2026 NFL preseason is in the books, and Week 2 is set to begin tonight with a pair of games. We are inching closer…
The Chargers have several position battles to settle and roster questions to answer. See who can claim roster spots or prove…
Week 1 of the NFL Preseason will begin on Thursday, and the final game of the night is an interconference showdown between the…
Follow all the Week 2 preseason action at SoFi Stadium.
The second preseason game for the San Francisco 49ers will take place tonight against the Los Angeles Chargers. They’ll get a…
The Chargers and 49ers faced off in a matchup that featured several standout performances, and plenty to take away from the game.
