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More than four years after its CAR-T star Carvykti’s initial FDA approval, Legend Biotech has reached a major milestone, posting its first profitable quarter. | Legend Biotech's interim CEO Alan Bash discusses competition from T-cell engagers and Gilead's new autologous CAR-T, as the Carvykti maker posted its first profitable quarter.
Legend Biotech posted Q2 profitability ($63M) on Carvykti CAR-T; J&J's bispecifics and Gilead's anito-cel raise competition. Myeloma's <10% BCMA penetration and CAR-T-first clinical preference secure runway; J&J partnership and manufacturing offset TCE threats.
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As Legend Biotech became profitable, the company is navigating the next phase of growth for its flagship CAR-T therapy, Carvykti.…

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