PEREIRA, Colombia (AP) — The search for life in the rubble of Colombia’s powerful earthquake grew more desperate on Wednesday as search teams pushed up against a key time threshold to locate survivors with signs of life.The devastation has tested Colombia’s new President Abelardo de la Espriella and his government as it scrambles to respond to the natural disaster and civil society as it pushes to provide aid to the vulnerable communities most affected by the quake. By Tuesday, de la Espriella said the 7.4 magnitude earthquake had killed at least 181 people and left 2,595 more injured in the west of the country. He said at least 195 remained missing, but civilian-run databases put that number closer to 4,000.Teams continued to pick through the rubble overnight in the hardest-hit cities of Cali, Pereira, Manizales and Quibdo, as time ticked away for victims to be found — and rescued — alive.

Aid agencies consider the first 48 to 72 hours crucial for retrieving survivors, though that threshold can be extended if they have access to food and water.Small successes have broken through the flattened buildings: rescuers pulling a dust-covered baby through a crack in a concrete wall and onlookers cheering as teams lift a woman onto a stretcher.In many areas, the official response to the devastation has been complicated by the ongoing crises of deep poverty and civil warfare that has forced displacement for decades.