Weight loss jabs like Mounjaro and Wegovy have now been linked to at least 216 UK deaths, the Daily Mail can reveal. The majority of victims are those who've used tirzepatide, the active ingredient in Mounjaro – which has been dubbed the 'King Kong' of slimming injections.Government figures also show a startling rise in deaths, with annual jab fatalities leaping by 300 per cent between 2024 and 2025 – from 22 to 94.Meanwhile, a total of 150,000 adverse reactions have been associated with the drugs since the earliest recorded figure in 2010 - 18,000 of which were serious or fatal.Most of these involve conditions affecting the gastrointestinal system, such as inflammation of the pancreas known as pancreatitis and gastroparesis, or stomach paralysis.The tallies, obtained via an analysis of official drug safety data, come days after an inquest heard that a 73-year-old British grandmother died after increasing her dose of Mounjaro.Caroline Savage's death was said to be faecal peritonitis, whereby bacteria leaks into the abdomen via a hole in the bowel.This often triggers life-threatening sepsis, and is fatal in half of patients who develop it. Weight loss jabs like Mounjaro and Wegovy have been linked to at least 216 UK deathsThe inquest heard that the slimming injections may increase pressure in the intestines in those with certain underlying conditions, increasing the risk of a hole forming – known medically as perforation.Experts have warned that patients should be aware of this lesser-known complication.Penny Ward, a pharmaceutical expert from King's College London, said that the jabs can cause the gut to work slowly, triggering a back-up of waste products that put pressure on the sensitive bowel lining, increasing the risk of a tear.She explained because this is 'not common' it is a lesser known potential side effect. 'Nausea and vomiting are quite common after taking these drugs, but severe, sudden onset of severe abdominal pain is an indication of something more worrisome going on and should be investigated,' she added. The Daily Mail has analysed reports made to the UK's medical safety regulator, the Medicines and Healthcare products Regulatory Agency (MHRA).These so-called Yellow Card reports are the UK's system for tracking suspected adverse drug reactions.They can be submitted from members of the public, healthcare professionals and those who work in the pharmaceutical industry.Officials stress that they do not prove that a medicine caused a reaction to happen, only that it is suspected by the individual making the report. Other health conditions may have been at play.