The best ergonomic mice can save you from the pain of repetitive strain injuries or even alleviate your existing pain caused by years of poor posture and contorting your wrists and hands on less-friendly input devices. Just because you bought one of the best laptops doesn’t mean your wrist will agree, as the touchpads aren’t the most comfortable way to navigate your system.

Fortunately for you, we’ve been testing some of the most popular and well-regarded ergonomic mice out there, and as veterans of writing tech reviews, we’ve developed actual needs for these computer mice, so we can tell you which actually help and which don’t. After putting 13 different models through their paces, we’ve found a new winner for the title of best ergonomic mouse as well as a top vertical pick for those who want something especially easy on their wrists.

Logitech MX Master 4 Mouse

Best ergonomic mouse

The Logitech MX Master 4 redefines ergonomics in mice by offering something for both mouse and trackpad users, thanks to the new Haptic Sense Panel. So, in addition to being one of the most comfortable mice we’ve ever used, it enables us to perform a ton of new commands with our thumbs without making them stretch or do much at all.