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Alnylam Pharmaceuticals’ stock price plummeted as much as 29% Thursday morning after disappointing Amvuttra sales and a lowered full-y | Alnylam’s stock price plummeted as much as 29% Thursday morning after disappointing Amvuttra sales and a lowered full-year forecast triggered fresh concerns over the ATTR franchise.
Alnylam's Amvuttra missed Q2 targets ($1.01B vs $1.05B expected), sparking a 29% stock drop and a $200M guidance cut. Competitive moats are widening as AstraZeneca's rival failed trials, but execution risk persists in reaching first-line market share targets.
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Alnylam cut its 2026 sales outlook despite a Q2 earnings beat as slower ATTR-CM market growth weighed on expectations and…

Alnylam cuts Amvuttra sales forecast ~$200M after misjudging market demand; stock drops premarket.

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Alnylam Lowers 2026 Outlook As Second-Line Amvuttra Demand Normalizes, Stock Tanks - Alnylam Pharmaceutic

Alnylam cuts Amvuttra sales guidance as demand shifts, hurting stock

Alnylam's stock is down 30% despite a booming biotech market. Here's why.

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