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Outpatient drug purchases under the 340B Drug Pricing Program crossed the $100 billion mark across 2025, a roughly 23% increase over the $81.4 billion of 2024, the Health Resources & Services A | The tally reflects a 23% increase over 2024, another substantial escalation in scale for the subsidy program critics say is being abused by large nonprofit hospitals.
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Hospitals often earn large spreads on high-volume branded drugs bought via 340B. Reforms may make hospitals more price-sensitive,…

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