RNAValidate: CPU-only validator for AI-predicted 3D RNA structures

RNAValidate: CPU-only validator for AI-predicted 3D RNA structures

A predictor-agnostic linter that checks AI-predicted 3D RNA structures against experimental data (FRET, cryo-EM, SHAPE/DMS probing, designability) — and flags the ones that will hydrolyze before you can measure them.

The gap

Predictors and designers (AlphaFold-3, RiboSphere, RoseTTAFold-RNA) are plentiful; an open-source, reproducible layer that audits a predicted 3D RNA structure against experimental evidence is not. Validating before synthesis saves thousands of USD per design.

What it does