US President Donald Trump posted a doctored image of himself with Italy's Prime Minister Giorgia Meloni with the caption "Restraining order needed" in the latest escalation between to the two leaders.

"People come and go but relations must endure," Italian Defence Minister Guido Crosetto told the news channel Sky TG24.

Foreign Minister Antonio Tajani also said he was "sure that transatlantic relations go well beyond individual comments."

Meloni did not respond personally.

Trump posted the photo with no caption so it's unclear what the restraining order comment refers to, but tensions flared between Washington and Rome at the end of June when Trump claimed Meloni had "begged" him for a picture together in an effort to boost her ratings.