Genetic biomarker linked to adverse outcomes in both ulcerative colitis, Crohn’s disease

The HLA-DRB1*01:03 allele was associated with severe outcomes across inflammatory bowel disease subtypes, including perianal complications, advanced therapy use and surgical interventions, according to study results. “The prognosis and clinical course of IBD is highly variable and largely unpredictable,” study author James C. Lee, PhD, MRCP, professor of basic and translational