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BRUSSELS: At least five people were killed and many more injured on Wednesday when a fire broke out in a high-rise apartment block in the Belgian port city of Antwerp, police said.

A fire service spokeswoman said it was not yet known what caused the blaze, which broke out mid-morning in the building of around 80 apartments on the bank of the river Scheldt.

“At least five people have lost their lives in the fire and many others have been seriously injured,” police spokeswoman Kim Bastiaens told Flemish public broadcaster VRT. She said rescue teams were still working to locate other possible victims.

Firefighters and medics deployed in large numbers to the scene, where television footage showed thick black smoke billowing from the upper floors of the building.