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Screening changes the trajectory entirely.
When hepatocellular carcinoma is detected early, patients may still be eligible for curative approaches such as ablation, resection, and transplant.
When it is diagnosed late, we more often are managing unresectable or advanced disease.
The American Society for Study of Liver Disease recommends he-hepatocellular carcinoma screening every six months with ultrasound and AFP in patients with cirrhosis and chronic hepatitis B populations.
