June 24, 2026
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The FDA has approved the first and only cyclin-dependent kinase 4/6 inhibitor for patients with HR-positive metastatic breast cancer, regardless of HER2 status. Palbociclib (Ibrance, Pfizer) was approved in combination with trastuzumab (Herceptin, Genentech), with or without pertuzumab (Perjeta, Genetech), and endocrine therapy as maintenance treatment for adults with HR-positive,
June 24, 2026
1 min read
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PATINA trial paved the way for palbociclib-based frontline maintenance regimen

FDA Approves Pfizer’s IBRANCE Regimen for HR+, HER2+ Metastatic Breast Cancer Frontline Maintenance

The FDA approves Pfizer's Ibrance regimen for HR+, HER2+ metastatic breast cancer maintenance after positive Phase 3 data.

The FDA has approved a new targeted therapy combination for the most common subtype of breast cancer.Gedatolisib (Revtorpyk,…

It’s been seven years since Pfizer scored an expansion for its breast cancer blockbuster Ibrance, and during that time, the drug…

Gedatolisib is approved in combination with fulvestrant, with or without palbociclib