Cadence Raises $100M Series C Led by Spark Capital to Automate Chronic Care
This new investment will help scale AI agents to meet the needs of over 56 million older adults with chronic disease amid a deepening clinician shortage.
Cadence, the clinical AI company managing chronic care for older adults, announced a $100 million Series C, amid adoption of its AI-powered care model across the nation's leading health systems.
The Series C was led by Spark Capital. Thrive Capital, General Catalyst, Coatue, B Capital, Corewell Health Ventures, Memorial Hermann, and Duke Health participated in the round.
Today, Cadence also announced new affiliations with Duke Health, a world-class academic health care system serving patients across North Carolina, and Texas Health Resources, the nonprofit health system that cares for more patients in North Texas than any other. Now working alongside over 20 leading health systems, Cadence treats more than 100,000 active patients, has demonstrated significant clinical improvements in peer-reviewed literature, and saves Medicare roughly $2.7 million every week1. The company tripled annual recurring revenue in 2025.













