VIDEO: Survival in metastatic invasive lobular carcinoma differs by mutational signature

CHICAGO — In this video, Sherry Shen, MD, discusses her presentation at ASCO Annual Meeting on mutational signatures and related outcomes in metastatic invasive lobular carcinoma.According to Shen, this subtype of breast cancer accounts for 10% to 15% of breast cancer diagnoses and is characterized by loss of the E-cadherin protein, which is responsible for cell-to-cell adhesion.