Stay up to date with notifications from The IndependentNotifications can be managed in browser preferences.Jump to contentThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged inAllNewsSportCultureLifestylePatients with severe lupus in the UK have achieved remission following a pioneering “immune reset” treatment using CAR T-cell therapy on the NHS. This marks the first time CAR T-cell therapy, previously used for cancer, has been applied to lupus in the UK, offering a potential cure and removing the need for lifelong medication. The single-dose therapy works by genetically modifying a patient's own cells to re-engineer the immune system to recognise and attack problematic cells, potentially removing the need for lifelong medication. A trial led by University College London Hospitals NHS Foundation Trust (UCLH) and University College London (UCL) saw five out of six severe lupus patients achieve remission within months. Experts describe the findings as “truly groundbreaking,” suggesting the therapy could deliver an immune reset and potentially offer a cure for lupus, though larger studies are needed. In fullGroundbreaking new NHS treatment sees patients go into remissionThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in
Groundbreaking therapy could revolutionise treatment for lupus
Stay up to date with notifications from The IndependentNotifications can be managed in browser preferences.Jump to contentThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged inAllNewsSportCultureLifestylePatients with severe lupus in the UK have achieved remission following a pioneering “immune reset” treatment using CAR T-cell therapy on the NHS. This marks the first time CAR T-cell therapy, previously used for cancer, has been applied to lupus in the UK, offering a potential cure and removing the need for lifelong medication. The single-dose therapy works by genetically modifying a patient's own cells to re-engineer the immune system to recognise and attack problematic cells, potentially removing the need for lifelong medication. A trial led by University College London Hospitals NHS Foundation Trust (UCLH) and University College London (UCL) saw five out of six severe lupus patients achieve remission within months. Experts describe the findings as “truly groundbreaking,” suggesting the therapy could deliver an immune reset and potentially offer a cure for lupus, though larger studies are needed. In fullGroundbreaking new NHS treatment sees patients go into remissionThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in
CAR T-cell therapy achieved remission in 5 of 6 lupus patients in UK NHS trial, first autoimmune application. Signals cell-engineering maturation and potential paradigm shift from chronic to one-time curative healthcare interventions.
