Meridian Bioscience and 4bases Announce Collaboration to Enable Rapid, Globally Scalable Next-Generation Sequencing Workflows
Ambient-stable NGS workflows, enabled by Meridian’s lyophilization expertise, expand global access to 4bases’ KaryoSolver™*, a platform for rapid structural variant analysis
The Life Science division of Meridian Bioscience, Inc., a leading global provider of diagnostic testing solutions and life science raw materials, today announced a collaboration with 4bases SA to support the global deployment of KaryoSolver, a next-generation cytogenetics assay, through advanced assay stabilization.
KaryoSolver represents a significant step forward in cytogenetics. Traditional workflows rely on multiple complementary tests, often taking days to deliver a complete picture. In contrast, KaryoSolver consolidates structural variant detection into a single assay with integrated data analysis, providing actionable genomic insights within hours.
However, bringing this innovation to a global market requires overcoming a critical barrier: reagent stability. Conventional liquid-based NGS library preparation solutions are inherently limited by short shelf life, creating significant challenges across the distribution chain, including the cost and complexity of refrigerated shipping and storage that have historically restricted scalable global expansion.
